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Objectives:To investigate the inhibition of dexamethasone on the hypersecretion of airway mucins in chronic bronchitis rats.

探讨地塞米松对慢性支气管道粘蛋白高分泌的抑制作用。

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Chronic bronchitis is actually lumped under the umbrella of chronic obstructive pulmonary disease (or COPD), along with emphysema.

性支气管炎与肺气肿同属于性阻塞型肺疾病(COPD、阻肺)。

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Osmosis-呼吸

Another effect of unchecked inflammation in alpha-1 antitrypsin deficiency is chronic bronchitis, resulting from increased mucus production and narrowing of the airways.

α-1抗胰蛋白酶缺乏导致炎失控的另果是性支气管炎,由黏液增多以及气道狭窄导致。

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Osmosis-呼吸

So alpha-1 antitrypsin deficiency can lead to both emphysema and chronic bronchitis, the two types of chronic obstructive pulmonary disease, or COPD.

因此α-1抗胰蛋白酶缺乏可导致肺气肿和,而肺气肿和支是阻肺(COPD)中的2种类型。

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Alright, so chronic bronchitis is a type of COPD that's diagnosed based on clinical symptoms, specifically coughing up a lot of mucus.

性支气管炎阻肺的种,它的诊断基于临床表现,特别是咳大量黏痰。

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Treatment of chronic bronchitis largely involves reducing risk factors, like for example stopping smoking, but also managing associated illnesses.

性支气管炎的治疗包括降低风险因,例如戒烟,还有治疗相关疾病状。

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People with chronic bronchitis also often present with hypoxemia, low oxygen in the blood, and hypercapnia, increased carbon dioxide in the blood.

患者经常合并有低,即气含量低,以及高碳酸,即中二化碳含量高。

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Even though an increased Reid index goes along with chronic bronchitis, the diagnosis is still done clinically and this measurement is not usually used diagnostically.

尽管支患者雷德指数会变大,这项检测很少用于临床诊断。

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Normally, this ratio should be less than 40%, but it can be over 40% for people with chronic bronchitis, because of the hyperplasia and hypertrophy of the glands.

般情况下应少于40%,对于患者来说,由于黏液腺的肥大增生,该数值会大于40%。

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TED-Ed(视频版)

Lung diseases like chronic bronchitis, emphysema, and asthma shrink the passageways that carry oxygen, while weakening the membrane that brings oxygen into the blood.

性支气管炎、肺气肿和哮喘等肺部疾病会缩小携带气的通道,同时削弱将气带入液的膜。

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TED-Ed(视频版)

COPD is a catch-all term to describe the most common breathing conditions, like emphysema and chronic bronchitis, which people often have at the same time.

COPD是统称, 用来描述最常见的呼吸系统疾病,如肺气肿和性支气管炎,这些疾病常常同时发生。

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As a result of having too much mucus and poorly functioning cilia, people with chronic bronchitis end up relying on coughing to get rid of their mucus plugs.

因为有太多痰液集聚,纤毛的功能也变差,病患者只能靠咳嗽来排除阻塞的痰液。

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Osmosis-呼吸

These two are different in that chronic bronchitis is defined by clinical features, like a productive cough, whereas emphysema is defined by structural changes —specifically enlargement of the air spaces.

区别于肺气肿,性支气管炎有明显的临床特征,例如排痰性咳嗽,而肺气肿以结构改变为主,具体来说就是气腔的扩大。

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Osmosis-呼吸

Other risk factors for chronic bronchitis include exposure to air pollutants like sulfur and nitrogen dioxide, exposure to dust and silica, as well as genetic factors like having a family history of chronic bronchitis.

性支气管炎的其他致病因素包括空气污染物,例如硫和二化氮、暴露于灰尘和硅土,当然还有遗传因素,例如有性支气管炎的家族史。

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And finally another consequence of mucus plugging in chronic bronchitis is that people can develop lung infections behind the mucus blockages in the airway, and these infections can worsen the pulmonary and cardiac symptoms.

性支气管炎中黏液阻塞导致的另果是患者气道中黏液阻塞的方可能会产生肺部感染,这又会加重肺部与心脏的状。

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Osmosis-呼吸

The increased CO2 levels in the blood can get so bad that some people develop cyanosis, which is a blue discoloration of the skin, and this is why patients with chronic bronchitis are sometimes referred to as blue bloaters.

中二化碳含量升高可能引起发绀,即患者的皮肤会变蓝,这就是为什么患者又被比做蓝鲱鱼。

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